VEGF promotes glycolysis in pancreatic cancer via HIF1α up-regulation
Shi Si
Xu Jin
Zhang Bo
Ji Shunrong
Xu Wenyan
Liu Jiang
Jin Ke-Tao
Liang Dingkong
Liang Chen
Liu Luming
Liu C.
Qin Yi
Yu Xianjun
· 2016
期刊名称：
Current Molecular Medicine
2016 年
16 卷
4 期
摘要：
Background: Vascular endothelial growth factor (VEGF) is highly expressed in many types of tumors, including pancreatic cancer. Tumor cellderived VEGF promotes angiogenesis and tumor progression. However, the role of VEGF in glucose metabolism remains unclear. Objective: We investigated the role and the underlying mechanism of VEGF in the glucose metabolism of pancreatic cancer cells. Method: Pancreatic cancer cells were stimulated with VEGF
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