A red emitting two-photon fluorescent probe for dynamic imaging of redox balance meditated by a superoxide anion and GSH in living cells and tissues
Liu Hong-Wen
Zhu Xiaoyan
Zhang Jing
Zhang Xiao-Bing
Tan Weihong
· 2016
摘要：
Cellular self-regulation of reactive oxygen species(ROS)stress via antioxidant repair plays an important role in maintaining the redox balance.The redox balance between reducing and oxidizing species within cells is significant in the regulation of a signal pathway and is achieved by a series of elaborate mechanisms.In this work,we employed our previously reported D-?€-A-structured naphthalene-BODIPY TBET platform to design an efficient two-photon fluorescent probe for dynamic monitoring of superoxide anion oxidative stress and the GSH reducing repair process.The probe displayed high energy transfer efficiency(91.4%),large pseudo-Stokes shifts upon one-photon excitation,and red fluorescence emission(??
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